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Phosphonates and phosphonic acids are organophosphorus compounds containing C?PO2 or C?PO2 groups . Phosphonic acids and phosphonate salts are typically white, nonvolatile solids that are poorly soluble in organic solvents, but soluble in water and common alcohols. Many commercially important compounds are phosphonates, including glyphosate, the herbicide "Roundup", and ethephon, a widely used plant growth regulator. Bisphosphonates are popular drugs for treatment of osteoporosis.