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Tiamenidine is a imidazoline compound that shares many of the pharmacological properties of clonidine. It acts as a centrally-acting ?1 and ?2 adrenergic receptor antagonist . In hypertensive volunteers, like clonidine, it significantly increased sinus node recovery time and lowered cardiac output. It was marketed by Sanofi-Aventis under the brand name Sundralen for the management of essential hypertension.