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Abiogenesis or biopoiesis or OoL , is the natural process of life arising from non-living matter, such as simple organic compounds. It is thought to have occurred on Earth between 3.8 and 4.1 billion years ago. Abiogenesis is studied through a combination of laboratory experiments and extrapolation from the characteristics of modern organisms, and aims to determine how pre-life chemical reactions gave rise to life on Earth.