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Acetylcholine is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter?a chemical released by nerve cells to send signals to other cells. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that interfere with acetylcholine activity are called anticholinergics.