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Nitromifene , developmental code names CI-728, CN-5518, CN-55945) is a nonsteroidal selective estrogen receptor modulator related to triphenylethylenes like tamoxifen that was never marketed. It is a mixture of - and -isomers that possess similar antiestrogenic activity. The drug was described in 1966. Along with tamoxifen, nafoxidine, and clomifene, it was one of the earliest SERMs.