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Trichinosis, trichinellosis or trichiniasis is a parasitic disease caused by roundworms of the genus Trichinella. Infection was once very common, but is now rare in the developed world. The incidence of trichinosis in the U.S. has decreased dramatically in the past century. During 2008-2010, an annual average of 20 cases per year were reported in the United States. Several subspecies cause human disease, but T. spiralis is the most known. Infection may occur without symptoms, while intestinal invasion can cause diarrhea, abdominal pain or vomiting. Larval migration into muscle tissue can cause edema of the face or around the eyes, conjunctivitis, fever, muscle pains, splinter hemorrhages, rashes, and peripheral eosinophilia. Life-threatening cases can result in myocarditis, central nervous system involvement, and pneumonitis. Larval encystment in the muscles causes pain and weakness, followed by slow progression of symptoms.