Suche

Deutsche Tryptamin {n} [chem.] Synonyme

chem  

Englische tryptamine Synonyme

tryptamine Definition

tryptamine Bedeutung

Ergebnisse der Bewertung:
130 Bewertungen 4

 

Einfach einen Begriff in der Tabelle rechts anklicken um weitere Übersetzungen in dieser Sidebar zu erhalten.

Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan.[2][3] The chemical structure is defined by an indole ? a fused benzene and pyrrole ring, and a 2-aminoethyl group at the third carbon.[2] The structure of tryptamine is a shared feature of certain aminergic neuromodulators including melatonin, serotonin, bufotenin and psychedelic derivatives such as dimethyltryptamine , psilocybin, psilocin and others.[2][4][5] [6] Tryptamine has been shown to activate trace amine-associated receptors expressed in the mammalian brain, and regulates the activity of dopaminergic, serotonergic and glutamatergic systems.[7] [8] In the human gut, symbiotic bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility.[3][9][10] Multiple tryptamine-derived drugs have been developed to treat migraines, while trace amine-associated receptors are being explored as a potential treatment target for neuropsychiatric disorders.[11][12][13]